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ProteomicsUnbiased characterization and systematic profiling of metabolically labeled RNA-binding sites
Here we introduce pRBS-ID, an amenable platform that enables robust profiling of PAR-crosslinked RBSs. Using tandem mass spectrometry (MS/MS) approaches, we unbiasedly characterize the PAR adducts on peptides, to develop an optimal MS/MS search pipeline that enables robust identification and quantif...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD023401 | Pride
Human Lc-ms/ms 
ProteomicsRBS-ID: Comprehensive identification of RNA-binding sites at single amino acid-resolution
We developed RBS-ID, which greatly simplifies the RNA moiety by chemical cleavage, reducing the complexity of MS/MS search space to accurately identify and localize RBS in peptides. RBS-ID comprehensively and robustly identifies RNA-binding sites at both proteome and single protein level.
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2020-06-02 | PXD016254 | Pride
Human Rbp. rbs Rna Lc-ms/ms 
MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
TranscriptomicsMajor Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), anti-CD40 (CD40L), LPS, and, to a l...
ORGANISM(S): Mus musculus 
2004-12-08 | E-GEOD-2050 | biostudies-arrayexpress
UnknownConservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Not available
S-EPMC7808565 | biostudies-literature
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