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Analysis of the Expression Change of RyhB Regulon in RyhB-deleted Mutant Strains. Wild-type Salmonella 14028 vs. three mutant strains (∆ryhB1, ∆ryhB2, and ∆ryhB1&∆ryhB2); One condition experiment, Iron-depleted condition by adding 200 µM of 2,2’-dipyridyl (dip).
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S 
In this study, integrated transcriptomics and proteomics approaches were applied to investigate the molecular responses of JA in the shoots of 7-days old rice (cv. Nipponbare) seedlings exposed to 5 micromolar JA for a period of 7 days. Based on the morphological alteration of JA-exposed rice seedli...
ORGANISM(S): Oryza sativa 
A genome-wide gene expression comparison between primary central nervous system lymphoma (PCNSL) and normal lymph node was performed to identify a differential exprssion and specific pathway. Experiment design: 7 PCNSL and 7 normal lymph node tissues were used for comparison.
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the following subset Series: GSE25297: Genome-wide gene expression comparison (primary central nervous system lymphoma (PCNSL) vs normal lymph node) GSE25298: Genomic aberrations in primary central nervous system lymphoma (PCNSL) Refer to individual Series
ORGANISM(S): Homo sapiens 
Cyclin-dependent kinase 7 (CDK7) plays a critical role in the general regulation of RNA polymerase II-mediated transcription. However, the absence of selective CDK7 inhibitors has hindered the ability to investigate the consequences of acute and prolonged inhibition of CDK7 under normal and patholo...
ORGANISM(S): Homo sapiens 

Background

Smoking is the leading behavioural risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking prevalence has slowed in recent years for many countries, and alth...

Background

Low dose corticosteroids (e.g., 6 mg dexamethasone) have been shown to reduce mortality for hypoxic COVID-19 patients. We have previously reported that higher dose corticosteroids cause harm in patients with clinical hypoxia but not receiving ventilatory support (the combination o...
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