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UnknownPhosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5).
Not available
S-EPMC552943 | biostudies-literature
UnknownA randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Not available
S-EPMC9283731 | biostudies-literature
UnknownImmobilized epidermal growth factor stimulates persistent, directed keratinocyte migration via activation of PLCγ1.
Not available
S-EPMC4904288 | biostudies-literature
UnknownKorean Multicenter Registry of ELUVIA Stent for Femoropopliteal Artery Disease: K-ELUVIA Registry.
Not available
S-EPMC11361770 | biostudies-literature
UnknownPre-transplant Evaluation of Donor Urinary Biomarkers can Predict Reduced Graft Function After Deceased Donor Kidney Transplantation.
Not available
S-EPMC4839919 | biostudies-literature
UnknownSex Differences in Outcomes Following Endovascular Treatment for Symptomatic Peripheral Artery Disease: An Analysis From the K- VIS ELLA Registry.
Not available
S-EPMC6497340 | biostudies-literature
GenomicsAKT phosphorylates H3-threonine 45 to facilitate termination of gene transcription in response to DNA damage.
Purpose: In this study, we show that DNA damage-activated AKT phosphorylates threonine 45 of core histone H3 (H3-T45) Result: By genome-wide chromatin immunoprecipitation sequencing (ChIP-seq) analysis, H3-T45 phosphorylation was distributed throughout DNA damage-responsive gene loci, particularly i...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-67699 | biostudies-arrayexpress
TranscriptomicsAkt-Induced Mitochondrial Dysfunction in the Heart
Sustained Akt activation induces cardiac hypertrophy (LVH), which may lead to heart failure. This study tested the hypothesis that Akt activation contributes to mitochondrial dysfunction in pathological LVH. Akt activation induced LVH and progressive repression of mitochondrial fatty acid oxidation ...
ORGANISM(S): Mus musculus 
2015-01-05 | E-GEOD-63848 | biostudies-arrayexpress
TranscriptomicsCell Intrinsic role of Cox-2 in pancreatic cancer development
Cyclooxygenase-2 (COX-2) is upregulated in pancreatic ductal adenocarcinomas (PDAC). However, how COX-2 promotes PDAC development is unclear. While previous studies have evaluated the efficacy of COX-2 inhibition via the use of non steroidal anti-inflammatory drugs (NSAIDs) or the COX-2 inhibitor ce...
ORGANISM(S): Mus musculus 
2012-06-28 | E-GEOD-38988 | biostudies-arrayexpress
UnknownA Traditional Korean Diet Alters the Expression of Circulating MicroRNAs Linked to Diabetes Mellitus in a Pilot Trial.
Not available
S-EPMC7551128 | biostudies-literature
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