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ProteomicsSirt2 inhibition reprograms T cell metabolism for optimal anti-tumor immunity: Sirt2 Interacting Proteins
Growing evidence indicates that metabolism is a key driver of T cell functions. A switch from oxidative phosphorylation to aerobic glycolysis is a hallmark of T cell activation and is required to meet metabolic demands of proliferation and effector functions. However, the mechanisms underlying the m...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-15 | PXD012811 | Pride
T cell Sirtuin 2 Metabolism Interacting proteins Glycolysis 
ProteomicsSirt2 inhibition reprograms T cell metabolism for optimal anti-tumor immunity: Lysine Acetylation
Growing evidence indicates that metabolism is a key driver of T cell functions. A switch from oxidative phosphorylation to aerobic glycolysis is a hallmark of T cell activation and is required to meet metabolic demands of proliferation and effector functions. However, the mechanisms underlying the m...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-15 | PXD012796 | Pride
T cell Sirtuin 2 Metabolism Acetylation Glycolysis 
ProteomicsSirt2 inhibition reprograms T cell metabolism for optimal anti-tumor immunity: Sirt2 Interacting Proteins 2
Growing evidence indicates that metabolism is a key driver of T cell functions. A switch from oxidative phosphorylation to aerobic glycolysis is a hallmark of T cell activation and is required to meet metabolic demands of proliferation and effector functions. However, the mechanisms underlying the m...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-03 | PXD020150 | Pride
T cell Sirtuin 2 Metabolism Interacting proteins Glycolysis 
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