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UnknownFurther evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.
Not available
S-EPMC2650371 | biostudies-literature
TranscriptomicsRNA-seq mouse development
The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly interact during protein synthesis; the stability and regulation of this interaction remains largely unexplored. Here, we quantitatively characterized the expression of mRNA and tRNA genes across developing mouse ti...
ORGANISM(S): Mus musculus 
2014-08-08 | E-MTAB-2328 | biostudies-arrayexpress
TranscriptomicsRNA-seq of liver tissue and liver cancer cell lines
This dataset has been designed to test whether codons in mRNAs and anticodons in tRNAs vary in order to maximize translation in specific cellular conditions in mammals. Prokaryotes and simple unicellular eukaryotes optimize their translational rates by adjusting the codons in the protein-coding tran...
ORGANISM(S): human 
2016-04-18 | E-MTAB-4052 | biostudies-arrayexpress
TranscriptomicsMolecular profile of parvalbumin-immunoreactive neurons in superior temporal cortex in schizophrenia
Dysregulation of pyramidal cell network function by the soma- and axon-targeting inhibitory neurons that contain the calcium-binding protein parvalbumin (PV) represents a core pathophysiological feature of schizophrenia. In order to gain insight into the molecular basis of their functional impairmen...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-46509 | biostudies-arrayexpress
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