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Transcriptional profiling of CD133+/high vs CD133-/low cell populations of Caco2, HT-29 and HUH7 cell lines. Further in silico analysis of differentially expressed transcripts and proteins in CD133+/high vs CD133-/low cell populations revealed several potential key molecular regulators of CD133. In ...
ORGANISM(S): Homo sapiens 
Self-renewing tumor initiating cells that are capable of differentiation and responsible for tumor growth have been isolated from cancers and cell lines. If such minor populations are associated with tumor progression, understanding molecular pathways that are required for viability and maintenance ...
ORGANISM(S): Homo sapiens 
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
2017-11-07 | MTBLS387 | MetaboLights
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