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ProteomicsDimeric IgA specifically disables intracellular mutated oncodrivers
Despite their long half-life, therapeutic antibodies are considered ineffective against intracellular antigens due to their perceived inability to penetrate epithelial cells. Using recombinant antibodies targeting common mutations in oncogenes, we demonstrate that dimeric IgA, but not the same antib...
ORGANISM(S): Homo Sapiens 
PXD044426 | panorama
TranscriptomicsDiscovery of novel recurrent mutations and rearrangements in early T-cell precursor acute lymphoblastic leukemia by whole genome sequencing
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-28703 | biostudies-arrayexpress
GenomicsQCMG_20130826 - samples
Analysis .bam files from HiSeq sequencing of Australian ICGC PDAC study samples, submitted 20130826
EGAD00001000660 | EGA
GenomicsQCMG20130201_pancreatic - samples
Sequencing data for Australian Pancreatic Cancer study submitted 20130102
EGAD00001000323 | EGA
GenomicsRNASeq_PACA-AU_Apr_2017 - samples
BAM outputs from RSEM (https://deweylab.github.io/RSEM/) analysis of RNASeq sequencing on HiSeq platform of tumour samples from 95 pancreatic adenocarcinoma cases.
EGAD00001003298 | EGA
GenomicsABO_OICR_DATASET - samples
OICR PANCREATIC CANCER DATASET
EGAD00001000262 | EGA
GenomicsQCMG_PDAC_cell_lines - samples
Sequencing data for PDAC cell lines generated by QCMG
EGAD00001000371 | EGA
GenomicsICGC_PACA-AU_20160429 - samples
Additional sequencing data for 173 donors in EGAS00001000154, a study of Pancreatic Ductal Adenocarcinoma. WGS libraries were used for high-cellularity cases, WXS sequencing to high depth on low-cellularity cases. HiSeq 2xxx platform was used in all cases. The analysis files associated with this dat...
EGAD00001002192 | EGA
GenomicsPancreatic adenocarcinoma QCMG 20120201 - samples
Pancreatic adenocarcinoma QCMG 20120201
EGAD00001000096 | EGA
GenomicsPancreatic adenocarcinoma QCMG 20110901 - samples
Pancreatic adenocarcinoma QCMG 20110901
EGAD00001000049 | EGA
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