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TranscriptomicsRIP-chip analysis of the C. elegans GLD-2 and RNP-8 protein
C. elegans GLD-2 forms an active PAP with multiple RNA-binding partners to regulate diverse aspects of germline and early embryonic development. One GLD-2 partner, RNP-8, was previously shown to influence oocyte fate specification. To identify transcripts selectively associated with both GLD-2 and R...
ORGANISM(S): Caenorhabditis elegans 
2010-09-21 | E-GEOD-23843 | biostudies-arrayexpress
TranscriptomicsRIP-Chip analysis of the C. elegans FOG-1 and FOG-3 proteins
FOG-1/CPEB and FOG-3/Tob are the terminal regulators of the sex determination in C. elegans germ cells. CPEB and Tob proteins are both translational regulators. To investigate how FOG-1 and FOG-3 regulate germ cell sex determination we sought to identify the target mRNAs. We used transgenic epito...
ORGANISM(S): Caenorhabditis elegans 
2015-12-14 | E-GEOD-73070 | biostudies-arrayexpress
TranscriptomicsA new dataset of spermatogenic vs oogenic transcriptomes in the nematode C. elegans
The nematode Caenorhabditis elegans is an important model for studies of germ cell biology, including specification as sperm or oocyte, the meiotic cell cycle and gamete differentiation. Fundamental to those studies is a genome-level knowledge of the germline transcriptome. Here we use RNA-Seq to ...
ORGANISM(S): Caenorhabditis elegans 
2014-07-29 | E-GEOD-57109 | biostudies-arrayexpress
TranscriptomicsA nuclear Argonaute promotes germline immortality and epigenetic inheritance across generations
dsRNA-mediated gene silencing (RNAi) can be inherited for multiple generations in C. elegans. To understand this process we conducted a genetic screen for animals defective for transmitting RNAi silencing signals to future generations. This screen identified the gene heritable RNAi defective (hrde)-...
ORGANISM(S): Caenorhabditis elegans 
2012-07-30 | E-GEOD-38041 | biostudies-arrayexpress
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