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GenomicsProper chromatin programming during spermatogenesis is required for embryonic development
Epigenetic mechanisms including DNA methylation, non-coding RNAs and histone modifications control gene expression. Studies suggest that a father's lifetime experiences can be transmitted to his offspring to affect development and health. The mechanisms underlying such epigenetic inheritance are unk...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-55471 | biostudies-arrayexpress
TranscriptomicsLow paternal dietary folate alters the sperm epigenome and is associated with negative pregnancy outcomes
Epidemiological studies suggest that a father’s diet can influence offspring health. A proposed mechanism for paternal transmission of environmental information is via the sperm epigenome. The epigenome includes heritable information such as DNA methylation. We hypothesized that the dietary suppl...
ORGANISM(S): Mus musculus 
2013-11-02 | E-GEOD-52017 | biostudies-arrayexpress
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