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ProteomicsEMG1 cooperates with GRHL3 in β-catenin–mediated surface ectoderm differentiation to regulate neural tube closure
Grainyhead-like transcription factor 3 (GRHL3) directs surface ectoderm differentiation under the control of the canonical Wnt/β-catenin pathway. However, the molecular mechanisms that control nuclear GRHL3 expression through β-catenin are not fully understood. Here, we show that the essential for m...
ORGANISM(S): Homo Sapiens (human) 
2025-07-01 | PXD056807 | JPOST Repository
UnknownUSP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.
Not available
S-EPMC9018712 | biostudies-literature
UnknownCytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.
Not available
S-EPMC6170465 | biostudies-literature
TranscriptomicsFate specification of neural plate border by canonical Wnt signaling and Grhl3 is crucial for neural tube closure.
During primary neurulation, the separation of a single-layered ectodermal sheet into the surface ectoderm (SE) and neural tube specifies SE and neural ectoderm (NE) cell fates. The mechanisms underlying fate specification in conjunction with neural tube closure are poorly understood. Here, by compar...
ORGANISM(S): Mus musculus 
2015-04-17 | E-GEOD-67977 | biostudies-arrayexpress
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