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Osteopontin Deficiency Amerliorates Alport Kindey Pathology
Genomics
Kindey transcriptome of three Syngnathidae species.
Role of cGAS-STING pathway in aging and sexual dimorphism in diabetic kindey disease
In this study, we try to identify dysregualted-genes in kindey with experimental membranous nephroapthy (MN).
ORGANISM(S): Mus musculus 
2018-03-13 | GSE69536 | GEO
Kidneys were snap frozen from 2 month old wild type, Col4a3-/-, or Col4a3-/-OPN-/- mice. RNA was isolated using Mirvana Paris kit.
ORGANISM(S): Mus musculus 
2018-01-30 | GSE109777 | GEO
epigenetic regulation plays a vital role in renal carcinogenesis. Here,we found epigenetic regulator MORC2 promoted carcinogenesis in kidney. Mechanistically, MORC2 functioned as oncogene via epigenetically silencing canonical tumor suppressor DAPK1 in kidney. Therefore, aMORC2—DAPK1 pro—oncogenic a...
ORGANISM(S): Homo sapiens 
2023-10-25 | GSE221129 | GEO
Methylome data obtained from human embryonic kindey (HEK)-293T cells expressing a GFP (293T-GFP) or a truncated form of Arabidopsis DEMETER (DME) 5-methylcytosine (5mC) DNA glycosylase (293T-DMEΔ) analyzed on a Human Methylation 450K BeadChip platform (Illumina). These methylation array data reveale...
ORGANISM(S): Homo sapiens 
2017-09-20 | GSE96864 | GEO
This work aimed to examine the regulation of apoptosis-related genes in kidney cortex and kindey medulla one and seven days after administration of 177Lu-octreotate with and without A1M and of A1M alone. C57BL/6N mice were injected with either 177Lu-octreotate + PBS, A1M + PBS or 177Lu-octreotate + ...
ORGANISM(S): Mus musculus 
2024-04-01 | GSE200619 | GEO
We investigated the cGAS-STING inflammatory pathway differential activity among both sexes in T2DN rats and its impact on the temporal progression of the diabetic kidney disease. Here we used both male and female old and young T2DN rats. The cGAS-STING pathway presented distinct protein expression p...
ORGANISM(S): Rattus norvegicus 
2023-09-13 | GSE243138 | GEO
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