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TranscriptomicsTranscription profiling of mouse cartilage tumours IGFBP-3 reveals is regulated by Gli signaling in cartilage tumors.
Mice that develop benign cartilage lesions due to overexpression of Gli2 in chondrocytes developed lesions similar to chondrosarcomas when also deficient in p53. Gli2 overexpression and p53 deficiency had opposing effects on chondrocyte differentiation, but had additive effects negatively regulatin...
ORGANISM(S): Mus musculus 
2009-03-14 | E-GEOD-15118 | biostudies-arrayexpress
TranscriptomicsInjury-dependent hydrogen peroxide oxidation of IKK-alpha regulates keratinocyte migration through induction of EGF
Hydrogen peroxide is known to promote skin keratinocyte migration, although the mechanism of action is unclear. In an attempt to identify signaling pathways regulated by hydrogen peroxide in the skin, 3 day post fertilized (dpf) zebrafish larvae (nacre strain) were treated with 3mM hydrogen peroxide...
ORGANISM(S): Danio rerio 
2016-02-22 | E-GEOD-75728 | biostudies-arrayexpress
TranscriptomicsLate-stage embryonic gene expression in three cartilaginous fishes
Gene expression profiling of pooled late stage embryos from Leucoraja erinacea, Scyliorhinus canicula and Callorhinchus milii show that HOXC cluster genes are not expressed in the two elasmobranch fishes, L. erinacea and S. canicula. This finding supports the observations that these genes are not f...
ORGANISM(S): Leucoraja erinacea 
2011-12-15 | E-GEOD-26235 | biostudies-arrayexpress
TranscriptomicsCortisol-treated zebrafish embryos develop into pro-inflammatory adults with aberrant immune gene regulation
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Danio rerio 
2016-06-01 | E-GEOD-80286 | biostudies-arrayexpress
TranscriptomicsSmall RNA and mRNA expression profiling during zebrafish caudal fin regeneration
Previous studies of zebrafish caudal fin regeneration have shown that multiple genetic programs are moduled through regulatory factors. MicroRNAs are short highly conserved non-coding genes that suppress expression of target genes and thereby control multiple genetic programs. Given their importan...
ORGANISM(S): Danio rerio 
2016-06-01 | E-GEOD-74415 | biostudies-arrayexpress
UnknownGenetic diversity of recently acquired and prevalent HIV, hepatitis B virus, and hepatitis C virus infections in US blood donors.
Not available
S-EPMC3282564 | biostudies-literature
UnknownYAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation.
Not available
S-EPMC7501173 | biostudies-literature
TranscriptomicsMicroRNA expression profiling of zebrafish heart regeneration
Cardiovascular disease is the leading cause of morbidity and mortality in the Western world due to a limited regenerative capacity. In lieu of new muscle synthesis, the human heart replaces necrotic tissue with deposition of a non-contractile scar. In contrast, the adult zebrafish is endowed with a ...
ORGANISM(S): Danio rerio 
2015-11-05 | E-GEOD-74494 | biostudies-arrayexpress
ModelsBand2012_DII-Venus_FullModel
This model is from the article: Root gravitropism is regulated by a transient lateral auxin gradient controlled by a tipping-point mechanism. Band LR, Wells DM, Larrieu A, Sun J, Middleton AM, French AP, Brunoud G, Sato EM, Wilson MH, Péret B, Oliva M, Swarup R, Sairanen I,...
2024-09-02 | BIOMD0000000413 | BioModels
TranscriptomicsResponse to low-dose cortisol treatment in zebrafish embryos [larvae]
Chronic early life stress increases adult susceptibility to numerous health problems linked to chronic inflammation. One way that this may occur is via glucocorticoid-induced developmental programming. To gain insight into such programming we treated zebrafish embryos with 1 micromolar cortisol and ...
ORGANISM(S): Danio rerio 
2016-06-01 | E-GEOD-80221 | biostudies-arrayexpress
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