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TranscriptomicsPancreatic Cancer 1
This is the experiment set used for a paper written in collaboration with Hopkins. It compares genes that are differentially expressed between normal pancreas, pancreatic cell lines and pancreatic adenocarcinoma. Pancreatic cancer is the fifth leading cause of cancer death in the United States. We u...
ORGANISM(S): Homo sapiens 
2005-11-23 | E-GEOD-3654 | biostudies-arrayexpress
TranscriptomicsTranscriptional signature of wounded keratinocytes reveals selective roles for ERK1/2, P38 and PI3K signalling pathways
Covering denuded dermal surface after injury requires migration, proliferation and differentiation of skin keratinocytes. To clarify the major traits controlling these intermingled biological events, we surveyed the genomic modifications occurring during the course of a scratch closure of cultured h...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-6820 | biostudies-arrayexpress
TranscriptomicsGene expression profile of PBMCs after intake of fish oil for seven weeks compared to high oleic sunflower oil
Fish oil supplementation has been shown to alter gene expression of mononuclear cells both in vitro and in vivo. However, little is known about the total transcriptomic profile in healthy subjects after intake of fish oil compared to a control group. The objective was to examine the gene expression ...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-48368 | biostudies-arrayexpress
TranscriptomicsEffect of human DAI expressed by an oncolytic vaccinia virus on the gene expression of tumor cells (HS294T) and monocytes (THP-1).
Human melanoma tumor cells (HS294T) and monocytes (THP-1) were infected with a double deleted (-VGF, -TK) oncolytic vaccinia virus expressing human DAI (DNA-dependent activator of interferon-regulatory factors). Total RNA was collected and gene expresson profiles were determined with Agilent microar...
ORGANISM(S): Homo sapiens 
2016-03-01 | E-GEOD-76208 | biostudies-arrayexpress
TranscriptomicsATF3 is a positive regulator of human IFN gene expression
The aim of this study was to identify genes regulated by IL-12, IL-18 and IFN-alpha during early differentiation of human Th1 cells Human cord blood CD4+ T cells were activated via TCR and cultured in the presence of IL-12, IFN-alpha or IL-12+IL-18. Cytokine induced gene expression was compared to a...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-20198 | biostudies-arrayexpress
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