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TranscriptomicsTranscription profiling of human lamina cribrosa cells in vitro treated with mechanical strain
The mechanical effect of raised intraocular pressure is a recognised stimulus for optic neuropathy in primary open angle glaucoma (POAG). Characteristic extra-cellular matrix (ECM) remodelling accompanies axonal damage in the lamina cribrosa (LC) of the optic nerve head in POAG. Glial cells in the l...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3166 | biostudies-arrayexpress
UnknownEffect of sodium-glucose co-transporter-2 inhibitors on survival free of organ support in patients hospitalised for COVID-19 (ACTIV-4a): a pragmatic, multicentre, open-label, randomised, controlled, platform trial.
Not available
S-EPMC11451207 | biostudies-literature
MetabolomicsNeuroactive metabolites and bile acids are altered in extremely premature infants with brain injury

The gut microbiome has been associated with pathological neurophysiological evolvement in extremely premature infants suffering from brain injury. The exact underlying mechanism and its associated metabolic signatures in infants are not fully understood. To decipher metab...

2023-12-30 | MTBLS7560 | MetaboLights
UnknownCohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe.
Not available
S-EPMC8679118 | biostudies-literature
UnknownEffect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC10214036 | biostudies-literature
UnknownA reference human induced pluripotent stem cell line for large-scale collaborative studies.
Not available
S-EPMC9782786 | biostudies-literature
UnknownDemographic, clinical, and service-use characteristics related to the clinician's recommendation to transition from child to adult mental health services.
Not available
S-EPMC9042957 | biostudies-literature
UnknownSafe and transparent introduction and evaluation of targeted axillary dissection in patients with node-positive breast cancer undergoing primary surgery: international consensus process.
Not available
S-EPMC12574671 | biostudies-literature
UnknownThe predictive ability of the 313 variant-based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant.
Not available
S-EPMC8460445 | biostudies-literature
UnknownResearching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
Not available
S-EPMC10289397 | biostudies-literature
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