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UnknownSGK phosphorylates Cdc25 and Myt1 to trigger cyclin B-Cdk1 activation at the meiotic G2/M transition.
Not available
S-EPMC6829662 | biostudies-literature
UnknownTwo new competing pathways establish the threshold for cyclin-B-Cdk1 activation at the meiotic G2/M transition.
Not available
S-EPMC5004895 | biostudies-literature
UnknownGene therapy with SOCS1 for gastric cancer induces G2/M arrest and has an antitumour effect on peritoneal carcinomatosis.
Not available
S-EPMC4522636 | biostudies-literature
UnknownThe Two-Faced Cytokine IL-6 in Host Defense and Diseases.
Not available
S-EPMC6274717 | biostudies-literature
TranscriptomicsIdentification of genes involved in macrophage activation and effector functions against Listeria monocytogenes.
Listeria monocytogenes (LM) is a Gram-positive, facultative intracellular bacterium responsible for disseminated infections in immunocompromised individuals which can result in septicaemia and meningitis (1). Effective control of listeriosis requires both innate and adaptive immune responses with th...
ORGANISM(S): Mus musculus 
2007-09-12 | GSE6256 | GEO
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Cell NAMPTi treatment)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7251 | MetaboLights
UnknownRabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production.
Not available
S-EPMC5035883 | biostudies-literature
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAMPT targeted therapy)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7252 | MetaboLights
MetabolomicsNiacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma (Mouse NAD targeted time-course)

NAMPT plays a major role in NAD biosynthesis in many cancers and is an attractive potential cancer target. However, factors dictating therapeutic efficacy of NAMPT inhibitors (NAMPTi) are unclear. We report that neuroendocrine phenotypes predict lung and prostate carcinoma vulnerability to NAMPTi...

2023-10-10 | MTBLS7253 | MetaboLights
UnknownUmbilical cord serum metabolomics identifies amino acid alterations associated with impaired linear growth in small for gestational age infants.
Not available
S-EPMC12304126 | biostudies-literature
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