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Signaling between cells in the Anterior (A) and Posterior (P) compartments directs Drosophila wing disc development and is dependent on expression of the homeodomain transcription factor Engrailed (En) in P cells. Downstream of en, posteriorly expressed Hedgehog (Hh) protein signals across the A/P ...
ORGANISM(S): Drosophila melanogaster 
Transdetermination study
Eye imaginal disc development
The Drosophila melanogaster gene Dscam can generate thousands of different ectodomains via mutual exclusive splicing of three large exon clusters. The isoform diversity plays a profound role in both neuronal wiring and pathogen recognition. However, it remained unexplored how many isoforms are indee...
ORGANISM(S): Drosophila melanogaster 
We used microarrays to detail the global gene expression changes following RNAi knock-down of dTip60 in Drosophila SL2 cells Experiment Overall Design: We compared SL2 cells treated with dTip60-RNAi with SL2 cells mock-treated with eGFP-RNAi to determine global gene expression changes by microarray ...
ORGANISM(S): Drosophila melanogaster 
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