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UnknownConvergent evolution in the assembly of polyubiquitin degradation signals by the Shigella flexneri IpaH9.8 ligase.
Not available
S-EPMC4256345 | biostudies-literature
UnknownSer(120) of Ubc2/Rad6 regulates ubiquitin-dependent N-end rule targeting by E3{alpha}/Ubr1.
Not available
S-EPMC3009855 | biostudies-literature
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
UnknownE1-E2 interactions in ubiquitin and Nedd8 ligation pathways.
Not available
S-EPMC3249083 | biostudies-literature
TranscriptomicsEffect of topographical micropatterning on human endothelial cells
Shear stress is known to regulate endothelial cell orientation along the direction of flow. We asked wither cellular patterning along, in the absence of shear could have similar biological effects as shear. We used DNA microarrays to examine the effect of cellular patterning on their transcriptome. ...
ORGANISM(S): Homo sapiens 
2012-11-29 | E-GEOD-42596 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse sex differences in response to Plasmodium chabaudi infection: involvement of gonadal steroids
The goal of this study was to examine whether immune responses to Plasmodium chabaudi infection differ between the sexes and are altered by the presence of gonadal steroids. Gonadally-intact males were more likely than intact females to die following P. chabaudi infection, exhibit slower recovery f...
ORGANISM(S): Mus musculus 
2008-11-22 | E-GEOD-4324 | biostudies-arrayexpress
UnknownRandomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aromatase inhibitor.
Not available
S-EPMC4881332 | biostudies-literature
UnknownAngiopoietin-2 Inhibition Rescues Arteriovenous Malformation in a Smad4 Hereditary Hemorrhagic Telangiectasia Mouse Model.
Not available
S-EPMC6478529 | biostudies-literature
UnknownElevated incidence of dental caries in a mouse model of cystic fibrosis.
Not available
S-EPMC3031584 | biostudies-literature
UnknownPrimary Results From the Understanding Outcomes With the S-ICD in Primary Prevention Patients With Low Ejection Fraction (UNTOUCHED) Trial.
Not available
S-EPMC7752215 | biostudies-literature
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