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ProteomicsProteomic analysis of pleomorphic dermal sarcoma
In this study, we aimed to unravel the molecular underpinnings of pleomorphic dermal sarcomas (PDS), rare skin tumors often seen in sun-exposed regions. Using mass spectrometry, we examined proteomic profiles of 20 samples of normal healthy skin tissue (SNT), 27 malignant melanomas (MM), 20 cutaneou...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD046388 | Pride
Immune evasion Protein analysis Fibroblastic lineage Pleomorphic dermal sarcoma (pds) 
TranscriptomicsMicroarray correpsonding to the paper manuscript titled: Targeted expression profiling of single disseminated cancer cells isolated from bone marrow of prostate cancer patients
Bone is the most frequent site of metastasis in prostate cancer (PCa) and patients with bone metastases are deemed incurable. Targeting prostate cancer cells that disseminated to the bone marrow (BM) prior to surgery and before metastatic outgrowth may therefore prevent lethal metastasis. This promp...
ORGANISM(S): Homo sapiens 
2014-10-20 | E-GEOD-59631 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of root tissue from rice grown on arsenite-spiked sediments
The experiment intended to identify biomarker genes for arsenite exposure in rice roots. These biomarker genes were tested as alternative endpoints in an sediment-contact test with rice (Brinke et al. Environ Sci Pollut R 22.16 (2015): 12664-12675)
ORGANISM(S): Oryza sativa Indica Group 
2017-10-01 | E-MTAB-5430 | biostudies-arrayexpress
UnknownNanoscale resolved mapping of the dipole emission of hBN color centers with a scattering-type scanning near-field optical microscope.
Not available
S-EPMC11831392 | biostudies-literature
Transcriptomics4C-seq to show the effects of insertion of STITCH into MYC+30kb and NEUROG2-65kb positions on the chromatin conformation in human iPSCs and differentiated neural progenitor cells
We reconstituted arrays of CTCF binding sites (L1, L2, L3, L4, R1, R2, and R3) and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By coupling STITCH with tetR linked to the KRAB domain to induce heterochromatin and disable the insulation, we developed a drug-...
ORGANISM(S): Homo sapiens 
2020-05-01 | E-MTAB-8492 | biostudies-arrayexpress
Transcriptomics4C-seq from viewpoint at MYC promoter (VP-MYC1 and VP-MYC2), in wild type (Hap) and variously modified alleles around the locus in human iPS cells.
We reconstituted arrays of CTCF binding sites (L1, L2, L3, L4, R1, R2 and R3) and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By coupling STITCH with tetR linked to the KRAB domain to induce heterochromatin and disable the insulation, we developed a drug-i...
ORGANISM(S): Homo sapiens 
2020-05-01 | E-MTAB-7668 | biostudies-arrayexpress
UnknownDormancy-inducing 3D engineered matrix uncovers mechanosensitive and drug-protective FHL2-p21 signaling axis.
Not available
S-EPMC11540038 | biostudies-literature
UnknownA Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids.
Not available
S-EPMC10002577 | biostudies-literature
UnknownIdentification of and Molecular Basis for SIRT6 Loss-of-Function Point Mutations in Cancer.
Not available
S-EPMC4618237 | biostudies-literature
UnknownStructure, Optical and Magnetic Properties of Two Isomeric 2-Bromomethylpyridine Cu(II) Complexes [Cu(C6H9NBr)2(NO3)2] with Very Different Binding Motives.
Not available
S-EPMC9866386 | biostudies-literature
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