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ProteomicsKLF5 co-immunoprecipitation mass spectrometry
Lineage plasticity is a hallmark of pancreatic ductal adenocarcinoma (PDAC) and contributes to tumor heterogeneity and therapeutic resistance. Here, we identify KLF5 as a dynamic master regulator of epithelial lineage identity in PDAC, with dichotomous roles in promoting either classical or basal-li...
ORGANISM(S): Homo sapiens (Human) 
2025-08-21 | PXD066112 | Pride
Klf5 co-ip pdac 
TranscriptomicsA combined genomic approach unveils the transcriptional basis of heterogeneity of human pancreatic ductal adenocarcinoma [RNA-seq]
The histological grade of carcinomas describes the ability of tumor cells to organize differentiated epithelial structures and has prognostic impact. Molecular control of differentiation in normal and cancer cells relies on lineage-determining transcription factors (TFs) that activate the repertoire...
ORGANISM(S): Homo sapiens 
2016-01-18 | E-GEOD-64558 | biostudies-arrayexpress
GenomicsA combined genomic approach unveils the transcriptional basis of heterogeneity of human pancreatic ductal adenocarcinoma.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-18 | E-GEOD-64560 | biostudies-arrayexpress
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