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OtherFeasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.
Data from ProteomeXchange, PXD ID: PXD001550. File: QE2_130117_OPL1013_TiOx_CRC_DLD1_3_130125023714.mzml. Published as part of J Proteomics. 2015 Apr 1. pii: S1874-3919(15)00103-7 . From the Abstract: {{i}} Robust phosphopeptide enrichment methods with minimal fractionation are required to profile ...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320014765 | GPMDB
Resource Reanalysis 
ProteomicsEvaluation of phospho-tyrosine antibodies for label-free phosphoproteomics
In the past decade multiple tyrosine kinase inhibitors (TKIs) have been implemented in standard treatment regimens for patients with cancer. Unfortunately the majority of patients develops resistance to these drugs. Reliable tools for analysis of pharmacodynamic effects and drug resistance mechanism...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080270 | MassIVE
ProteomicsEarly-stage cancer biomarkers uncovered in the blood platelet proteome
Platelets play an important role in tumor growth and at the same time, platelet characteristics are affected by cancer presence. Therefore, we investigated whether the platelet proteome can be used as a source for biomarkers of early-stage cancer. Patients with early-stage lung (n=8) and head of pan...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-29 | MSV000082867 | MassIVE
ProteomicsHuman AML secretome and exosomes and correlation with Anti-Apoptotic Index, part 3
Expression of proteins regulating apoptosis (BCL-2, MCL-1, BCL-X and BAX) in acute myeloid leukemia (AML) blasts at diagnosis have been shown to be associated with disease-free survival. We previously found that the initially high apoptosis-resistance of AML cells decreased after therapy, while rega...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080268 | MassIVE
ProteomicsHuman AML secretome and exosomes and correlation with Anti-Apoptotic Index, part 4
Expression of proteins regulating apoptosis (BCL-2, MCL-1, BCL-X and BAX) in acute myeloid leukemia (AML) blasts at diagnosis have been shown to be associated with disease-free survival. The concentrations of these proteins are combined in the Anti Apoptotic index (AAI). We previously found that th...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-10-21 | MSV000080266 | MassIVE
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