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ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 6/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Mus musculus (Mouse) synthetic construct 
2025-02-26 | PXD036668 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 5/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): synthetic construct 
2025-02-26 | PXD036666 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 3/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD036661 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 4/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-02-26 | PXD036662 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
ProteomicsFlycodes enable preclinical analysis of dozens of antibodies using single cassette-dosed mice. Dataset 1/6
During discovery and development of protein-based drugs, extensive animal testing is required for preclinical analysis of pharmacokinetics, tissue biodistribution, toxicity, etc. Generally, several animals are required for testing a single drug. We show that the use of genetically encoded peptide ba...
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD036658 | Pride
Drug development Antibodies Peptide barcodes Cassette dosing 
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