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TranscriptomicsThe effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity
Background: Pyrazinamide (PZA) plays an essential part in the shortened 6-month tuberculosis (TB) treatment course due to its activity against slow-growing, semi-dormant organisms. We tested the paradigm that PZA preferentially targets slow growing cells of Mycobacterium tuberculosis that remain aft...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-03-25 | E-MTAB-4093 | biostudies-arrayexpress
UnknownOn the origin and evolution of apomixis in Boechera.
Not available
S-EPMC4086248 | biostudies-literature
TranscriptomicsComparative transcriptome of S. aureus strains
We report the transcriptome profiles (RNA seq) of three different co-isolates of S.aureus that have been identified and isolated in both laboratory and infective scenarios. The transcriptome profiles were generated by deep sequencing and transcript levels assessed. For this the raw reads underwent q...
ORGANISM(S): Staphylococcus aureus subsp. aureus USA300 
2014-10-13 | E-GEOD-49636 | biostudies-arrayexpress
TranscriptomicsEvolutionary conserved mutations in PhoPR attenuate the virulence of animal-adapted tuberculosis strains for humans
By genome comparison of 30 MTBC strains, we identified three SNPs affecting the phoPR genes of members of the animal and M. africanum lineages that were not seen in the M. tuberculosis sensu-stricto genomes. The genes phoPR encode a two component regulatory system that is known for its strong impact...
ORGANISM(S): Mycobacterium tuberculosis 
2014-07-07 | E-GEOD-54421 | biostudies-arrayexpress
UnknownSARS-CoV-2 wastewater genomic surveillance: approaches, challenges, and opportunities.
Not available
S-EPMC12794521 | biostudies-literature
UnknownFuture cancer research priorities in the USA: a Lancet Oncology Commission.
Not available
S-EPMC6178838 | biostudies-literature
UnknownInternational Delphi Expert Consensus on Safe Return to Surgical and Endoscopic Practice: From the Coronavirus Global Surgical Collaborative.
Not available
S-EPMC8189258 | biostudies-literature
UnknownHaptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation.
Not available
S-EPMC10289236 | biostudies-literature
UnknownThe evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
Not available
S-EPMC9529057 | biostudies-literature
UnknownGlobal Burden of Cardiovascular Diseases and Risks, 1990-2022.
Not available
S-EPMC7615984 | biostudies-literature
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