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TranscriptomicsGenome-Wide Gene Expression Profiles in the Pancreatic Lymph Nodes of At-Risk Autoantibody Positive Individuals
Type 1 diabetes (T1D) is a polygenic autoimmune disorder caused by autoreactive T cells that recognize pancreatic islet antigens and subsequently destroy insulin-producing β-cells. Pancreatic lymph nodes (PLN) are an essential site for the development of T1D, where tolerance to pancreatic self-antig...
ORGANISM(S): Homo sapiens 
2015-03-03 | E-GEOD-66413 | biostudies-arrayexpress
TranscriptomicsPLN tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice.
41K whole genome oligo-microarrays (Agilent Technologies) were used to characterize age-dependent changes in gene expression in pancreatic lymph nodes (PLN) obtained from up to 7 individual NOD mice at 6 different time points (10 days (n=7), and 4 weeks (n=6), 8 weeks (n=4), 12 weeks (n=7), 16 weeks...
ORGANISM(S): Mus musculus 
2009-03-10 | E-GEOD-15150 | biostudies-arrayexpress
TranscriptomicsPBC tissue- and age-specific changes in gene expression during disease induction and progression in NOD mice.
41K whole genome oligo-microarrays (Agilent Technologies) were used to characterize age-dependent changes in gene expression in peripheral blood cells (PBC) obtained from up to 8 individual NOD mice at 6 different time points (10 days (n=8), and 4 weeks (n=3), 8 weeks (n=7), 12 weeks (n=8), 16 weeks...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-21897 | biostudies-arrayexpress
TranscriptomicsGenome-Wide Gene Expression Profiles in the Pancreatic Lymph Nodes of non-obese diabetic (NOD) mice
Type 1 diabetes (T1D) is a polygenic autoimmune disorder caused by autoreactive T cells that recognize pancreatic islet antigens and subsequently destroy insulin-producing β-cells. Pancreatic lymph nodes (PLN) are an essential site for the development of T1D, where tolerance to pancreatic self-antig...
ORGANISM(S): Mus musculus 
2015-03-09 | E-GEOD-66658 | biostudies-arrayexpress
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