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UnknownIn-silico and in-vitro study of novel antimicrobial peptide AM1 from Aegle marmelos against drug-resistant Staphylococcus aureus.
Antimicrobial peptides have garnered increasing attention as potential alternatives due to their broad-spectrum antimicrobial activity and low propensity for developing resistance. This is for the first time; proteome sequences of Aegle marmelos were subjected to in-silico digestion and AMP predicti...
S-EPMC11519352 | biostudies-literature
UnknownMillennial-scale microbiome analysis reveals ancient antimicrobial resistance conserved despite modern selection pressures.

Background

Antimicrobial resistance presents a formidable challenge, yet its existence predates the introduction of antibiotics. Our study delves into the presence of antimicrobial resistance genes (ARGs) in ancient permafrost microbiomes, comparing them with contemporary soil and pristine e...
S-EPMC11657988 | biostudies-literature
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