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TranscriptomicsThe TSC/mTOR pathway regulates the innate inflammatory response
The TSC/mTOR (tuberous sclerosis complex/mammalian target of rapamycin) pathway has a central role in cell growth and is involved in human tumorigenesis. Here, we demonstrate an unexpected role of TSC2 and mTOR in regulating key inflammatory cytokines in monocytes, macrophages, and dendritic cells a...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-6002 | biostudies-arrayexpress
TranscriptomicsContribution of the STAT1alpha and STAT1beta isoforms to IFN-gamma mediated innate immunity
The transcription factor STAT1 is essential for interferon- (IFN) mediated protective immunity in humans and mice. Two splice isoforms of STAT1, STAT1M-NM-1 and STAT1M-NM-2, differ with regard to a C-terminal transactivation domain, which is absent in STAT1M-NM-2. Dimers of STAT1M-NM-2 are therefore...
ORGANISM(S): Mus musculus 
2014-04-04 | E-GEOD-48970 | biostudies-arrayexpress
UnknownHealthy from the Start: Co-Designing Sleep, Nutrition and Physical Activity Resources for Young Shiftworkers-Novel Implementation and Evaluation.
Not available
S-EPMC11474620 | biostudies-literature
UnknownEffect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial.
Not available
S-EPMC7139271 | biostudies-literature
UnknownIdentification of Racial Inequities in Access to Specialized Inpatient Heart Failure Care at an Academic Medical Center.
Not available
S-EPMC7183732 | biostudies-literature
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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