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TranscriptomicsInfluenza H3N2 infection of the Collaborative Cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice (blood)
To determine if genetic background can modulate severity of an infection, we studied the host responses to influenza infections in the eight genetically highly diverse Collaborative Cross (CC) founder mice. The CC founder (C57BL/6J, 129S1/SvlmJ, CAST/EiJ, PWK/PhJ) were intranasally infected with inf...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-74073 | biostudies-arrayexpress
TranscriptomicsInfluenza H3N2 infection of the Collaborative Cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice (lung)
To determine if genetic background can modulate severity of an infection, we studied the host responses to influenza infections in the eight genetically highly diverse Collaborative Cross (CC) founder mice. The CC founder (C57BL/6J, 129S1/SvlmJ, CAST/EiJ, PWK/PhJ) were intranasally infected with inf...
ORGANISM(S): Mus musculus 
2015-12-31 | E-GEOD-74074 | biostudies-arrayexpress
UnknownMolecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP.
Not available
S-EPMC7164119 | biostudies-literature
UnknownOf mice and men: the host response to influenza virus infection.
Not available
S-EPMC6132725 | biostudies-literature
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S-EPMC8564733 | biostudies-literature
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Not available
S-EPMC2990212 | biostudies-literature
UnknownExchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice.
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S-EPMC6230768 | biostudies-literature
UnknownTMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.
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S-EPMC6130959 | biostudies-literature
UnknownOP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential.
Not available
S-EPMC7778630 | biostudies-literature
UnknownInfluenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
Not available
S-EPMC4769537 | biostudies-literature
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