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TranscriptomicsRecurrent mutations of multiple components of cohesin complex in myeloid neoplasms
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-07-15 | E-GEOD-47684 | biostudies-arrayexpress
TranscriptomicsExon level expression profiling of mutant U2AF35 transduced HeLa cells
In this study, to obtain the biological impact of the mutated U2AF35, HeLa cells were retrovirally transduced with either mock, wild-type or S34F mutant of U2AF35, and Exon array was performed. Exon level analysis was performed for mock, wild-type U2AF35 or S34F mutant transduced HeLa in triplicate.
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31171 | biostudies-arrayexpress
TranscriptomicsExpression analysis of mutant U2AF35 transduced cells
In this study, to obtain the biological impact of the mutated U2AF35, HeLa and TF-1 cells were retrovirally transduced with either mock, wild-type or S34F mutant of U2AF35, and Expression array was performed. Expression analysis was performed for mock, wild-type U2AF35 or S34F mutant transduced HeLa...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31172 | biostudies-arrayexpress
TranscriptomicsExpression analysis of mock- or RAD21-transduced Kasumi1 cells
We recently identified recurrent mutations of cohesin complex in myeloid neoplasms through whole-exome sequencing analysis. RAD21 is one of the main components of the cohesin complex. In this study, to investigate the biological impact of wild-type RAD21 on Kasumi1 cells harboring RAD21 mutation, Ka...
ORGANISM(S): Homo sapiens 
2013-07-16 | E-GEOD-47641 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for myelodysplastic syndromes (MDS) and related neoplasms
In this study, to obtain a complete registry of genetic lesions in MDS and to identify novel therapeutic targets, we performed SNP array analysis and whole exome analysis for novel mutations using high-throughput sequencing technologies. In whole exome analysis, paired CD3-positive T cells were used...
ORGANISM(S): Homo sapiens 
2011-09-11 | E-GEOD-31174 | biostudies-arrayexpress
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