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Proteomics,MultiomicsComplementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproduction
The mammalian Y chromosome plays a critical role in spermatogenesis. However, the exact functions of each gene in the Y chromosome have not been completely elucidated, partly owing to difficulties in gene targeting analysis of the Y chromosome. Zfy was first proposed to be a sex determination factor...
ORGANISM(S): Mus <mouse, Genus> (ncbitaxon:10088) 
2016-11-24 | MSV000080355 | MassIVE
TranscriptomicsTranscriptome in alveolar epithelial type II-like cells differentiated from human lung progenitor cells
Resident stem/progenitor cells in lungs are important for tissue homeostasis and repair. We isolated human lung progenitor cells and named alveolar epithelial progenitor cells (AEPCs)(Fujino N, et al. 2011. Lab Invest. 91:363). AEPCs have phenotypes of both alveolar epithelial type II (ATII) cells a...
ORGANISM(S): Homo sapiens 
2012-10-11 | E-GEOD-33825 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of IdHP cells compared to LKS, Control ProB and E2A-/- progenitors
Self-renewal potential and multipotency are hallmarks of the stem cell1-3. It is generally conceived that acquisition of such a stemness requires rejuvenation of somatic cells through reprogramming of genetic and epigenetic status. We show here that a simple blockage of cell differentiation is suffi...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-46158 | biostudies-arrayexpress
TranscriptomicsCircadian and diurnal expression data of Synechococcus
In the unicellular cyanobacterium, Synechococcus elongatus PCC 7942, essentially all promoter activities are under the control of the circadian clock in continuous light (LL) conditions. Here, we employed high-density oligonucleotide arrays to explore comprehensive profiles of genome-wide Synechococ...
ORGANISM(S): Synechococcus elongatus PCC 7942 
2009-07-31 | E-GEOD-14225 | biostudies-arrayexpress
TranscriptomicsCD133+ cells contain cancer stem cell-like properties in Malignant Mixed Mullerian Tumor (Carcinosarcoma) of the Uterus
Cancer stem cells (CSCs) that display tumor-initiating properties have recently been identified. We herein identify and characterize CSCs in human uterine carcinosarcoma, a highly aggressive and therapy-resistant gynecologic malignancy, which is considered to be of mesodermal origin. FU-MMT-1, a c...
ORGANISM(S): Homo sapiens 
2013-02-10 | E-GEOD-27172 | biostudies-arrayexpress
TranscriptomicsComparison of human Rheumatoid arthritis patient peripheral whole blood mRNAs just before and after Leukocytapheresis
Leukocytapheresis((LCAP) is a safe, unique therapy prevalent for intractable rheumatoid arthritis even in case of drug allergy or infectious state. To investigate how to improve LCAP efficacy, we have conducted genes expressions analysis from peripheral blood of Rheumatoid arthritis patients using h...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-30662 | biostudies-arrayexpress
TranscriptomicsTranscriptional Mediator Subunit MED1/TRAP220 in Stromal Cells Is Involved in Hematopoietic Stem/Progenitor Cell Support through Osteopontin Expression
MED1/TRAP220, a subunit of the transcriptional Mediator/TRAP complex, is crucial for various biological events through its interaction with distinct activators such as nuclear receptors and GATA family activators. In hematopoiesis, MED1 plays a pivotal role in optimal nuclear receptor-mediated myelo...
ORGANISM(S): Mus musculus 
2010-08-31 | E-GEOD-22471 | biostudies-arrayexpress
TranscriptomicsDDX20 knockdown effect on hepatocellular carcinoma cells
Analysis of DDX20 knockdown - hepatocellular carcinoma cells. The expression levels of genes driven by NF-kB and related with carcinogenesis, were significantly enhanced in DDX20-knockdown cells. One condition experiment, HepG2 vs. HepG2-DDX20 knockdown cells
ORGANISM(S): Homo sapiens 
2012-07-14 | E-GEOD-28088 | biostudies-arrayexpress
UnknownPrediction of Opioid-Induced Respiratory Depression on Inpatient Wards Using Continuous Capnography and Oximetry: An International Prospective, Observational Trial.
Not available
S-EPMC7467153 | biostudies-literature
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