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ProteomicsRapid and Label-Free Structural Proteomics by One-Step Swift Trypsin LiP-MS
We developed a rapid, surface-targeted limited proteolysis workflow, Swift Trypsin LiP-MS (STLiP-MS), to profile proteome-wide structural changes under near-native conditions. STLiP-MS uses a trypsin-immobilized spin column and centrifugation-controlled contact to achieve instantaneous, highly repro...
ORGANISM(S): Homo Sapiens (human) Cellular Organisms 
2026-01-05 | PXD069771 | JPOST Repository
ProteomicsDemonstration of a complementary approach for genetic diagnosis of inborn errors of immunity using proteogenomic analysis
Genetic diagnosis plays a central role in the clinical management of patients with inborn errors of immunity (IEI). We proposed a novel method for diagnosing IEI using PBMC proteomics integrated with targeted RNA sequencing, providing notable insights into the pathogenesis of IEI. Data-independent a...
ORGANISM(S): Homo Sapiens (human) 
2023-11-25 | PXD038352 | JPOST Repository
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