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TranscriptomicsA gene expression profile of BRCAness that is associated with outcome in ovarian cancer
A gene expression profile of BRCAness was defined in publicly available expression data of 61 patients with epithelial ovarian cancer (34 patients with BRCA-1 or BRCA-2 mutations and 27 patients with sporadic disease). This dataset is publicly available at http://jnci.oxfordjournals.org/cgi/content/...
ORGANISM(S): Homo sapiens 
2010-07-11 | E-GEOD-19829 | biostudies-arrayexpress
TranscriptomicsExpression data from SKOV3 cells treated with SAHA or vehicle control
We performed a microarray experiment to assess SAHA-induced changes in expression of genes of the homologous recombination DNA repair pathway SKOV-3 ovarian cancer cells were treated with 1µM SAHA or vehicle-control (0.01% DMSO) for 6 or 24 hours, harvested and processed for RNA isolation. Data fo...
ORGANISM(S): Homo sapiens 
2014-03-19 | E-GEOD-53603 | biostudies-arrayexpress
TranscriptomicsExpression data from patients with advanced ovarian cancer
Integration of several ovarian cancer datasets to identify a reproducible predictors of survival Four microarray datasets from different institutions were reprocessed in a uniform manner, into a single training dataset. Survival analysis was performed and a validation cohort (61 patients from 3 inst...
ORGANISM(S): Homo sapiens 
2011-06-15 | E-GEOD-19161 | biostudies-arrayexpress
TranscriptomicsExpression data from mammary epithelial cells from BRCA1 mutation carriers and non BRCA1 mutation carriers
Female BRCA1 mutation carriers have a nearly 80% probability of developing breast cancer during their life-time. We hypothesized that the breast epithelium at risk in BRCA1 mutation carriers harbors mammary epithelial cells (MECs) with altered proliferation and differentiation properties. Microarray...
ORGANISM(S): Homo sapiens 
2008-11-19 | E-GEOD-13671 | biostudies-arrayexpress
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