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Tissue-resident macrophages comprise heterogeneous populations with unique functions and distinct gene expression signatures. While it has been established that they mostly originate from embryonic progenitors, the signals inducing a characteristic tissue-specific differentiation program remain unkn...
ORGANISM(S): Mus musculus 
Tissue-resident macrophages comprise heterogeneous populations with unique functions and distinct gene expression signatures. While it has been established that they mostly originate from embryonic progenitors, the signals inducing a characteristic tissue-specific differentiation program remain unkn...
ORGANISM(S): Mus musculus 
Inflammation is a very powerful innate immune response to tissue injury; however, it needs to be tightly regulated to prevent protracted and potentially damaging inflammation. In this project we study the impact of a negative regulator of IL-1 signaling that can be produced by different immune cell ...
ORGANISM(S): Mus musculus 
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