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GenomicsGene expression profiling of Eed knockout and Ezh2 knockout small intestinal crypts [ChIP-seq]
Polycomb-mediated gene repression plays an important role in adult stem cell maintenance. Direct targets of the Polycomb repressive complex PRC2 in th intestinal epithelium were revealed by performing ChIP-sequencing on crypt samples isolated from wild type murine small intestines. The resulting lis...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-81577 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of Eed knockout and Ezh2 knockout small intestinal crypts [RNA-seq]
Polycomb-mediated gene repression plays an important role in adult stem cell maintenance. We knocked out (using the inducible AhCre-LoxP system) Polycomb genes Eed and Ezh2 in the intestine for 6 weeks, after which crypts - the small intestinal stem cell zone - were harvested and RNA sequenced. We f...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-81576 | biostudies-arrayexpress
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