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TranscriptomicsEffects of PD-0332991 on gene expression of human pancreatic ductal adenocarcinoma (PDAC) cell lines
PD-0332991 is a small molecule inhibitor for Cdk4 and Cdk6. It exerted growth inhibitory effects on PDAC cell lines (AsPC-1 and COLO-357). Microarray analysis was used to characterize the changes in gene expression profiles of AsPC-1 and COLO-357 upon PD-0332991 incubation AsPC-1 and COLO-357 cells ...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-39646 | biostudies-arrayexpress
TranscriptomicsRB Dysfunction in Pancreatic Cancer Enables TGF-beta to Promote Proliferation
Pooled KRC (LSL-KrasG12D; Rb1L/L; Pdx1-Cre: oncogenic Kras and deleted Rb1 in the pancreas) cells derived from 2 month old mice were compared to pooled KC (LSL-KrasG12D; Pdx1-Cre: oncogenic Kras in the pancreas) cells derived from 8 month old mice.
ORGANISM(S): Mus musculus 
2014-02-09 | E-MEXP-3988 | biostudies-arrayexpress
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