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TranscriptomicsRNAseq of human Ewing, MSC, fibroblast cell lines - A side population of Ewing cells exhibits stem cell properties
Ewings Sarcoma (ES) belongs to the group of bone cancers defined by the existence of a certain EWS-ETS fusion gene. In this study we use the model cell line CADO-ES1 (EWSR1-ERG fusion gene) to characterize the tumor biology of a versatile ES side-population (SP). We aim to compare SP- and non-SP-cel...
ORGANISM(S): Homo sapiens 
2017-10-31 | E-MTAB-6067 | biostudies-arrayexpress
TranscriptomicsGenomic heterogeneity of osteosarcoma - implementing order on the level of functional modules
Osteosarcoma (OS) represents the most common pediatric bone cancer with complex karyotypes. On the genomic level a highly variable degree of alterations in nearly all chromosomal regions and between individual tumors is observable. This hampers the identification of common drivers in OS biology. To ...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-MTAB-3034 | biostudies-arrayexpress
GenomicsDNAseq of human Ewing cell line - CADO-ES1
Ewings Sarcoma (ES) belongs to the group of bone cancers defined by the existence of a certain EWS-ETS fusion gene. In this study we use the model cell line CADO-ES1 (EWSR1-ERG fusion gene) to characterize the genomic structure in respect to CNV and fusion gene events.
ORGANISM(S): Homo sapiens 
2017-10-02 | E-MTAB-6111 | biostudies-arrayexpress
TranscriptomicsGene x environment effect of serotonin transporter genotype and acute stressor on amygdala gene expression
The amygdala is a prominent region of the brain processing stress-related emotion and vigilance. Additionally it is known that the serotonergic system is strongly involved in stress response and adaptation. The serotonin transporter (5-HTT) as key regulator of serotonergic activity in the brain is a...
ORGANISM(S): Mus musculus 
2013-03-13 | E-GEOD-40393 | biostudies-arrayexpress
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