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TranscriptomicsDose and temporal effects of Phenobarbital on the liver miRNAome of male Fischer rats
Male Fischer rats were fed a control diet or a diet supplemented with 50, 500 or 1000 ppm Phenobarbital. The 500 and 1000 ppm PB doses induced a transient hyperplasia and a sustained hepatomegaly in treated animals. The animals were sacrificed and liver miRNAome was profiled in three animals per gro...
ORGANISM(S): Rattus norvegicus 
2013-07-03 | E-GEOD-48489 | biostudies-arrayexpress
TranscriptomicsEffect of treatment for three months with chemical carcinogen and non-carcinogens on liver miRNAome
Here, we examined the liver microRNA profile of male Fischer rats exposed through their diet to genotoxic (2-acetylaminofluorene) and epigenetic (phenobarbital, diethylhexylphthalate, methapyrilene HCL, monuron, and chlorendic acid) chemical hepatocarcinogens, as well as to non-hepatocarcinogenic tr...
ORGANISM(S): Rattus norvegicus 
2013-07-03 | E-GEOD-48492 | biostudies-arrayexpress
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