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TranscriptomicsEngineering Corynebacterium glutamicum for fast production of lysine and pipecolic acid
The Gram-positive soil bacterium Corynebacterium glutamicum is widely used in industrial fermentative processes for the production of amino acids. The world production of L-lysine has surpassed 2 million tons per year. Glucose is taken up into the C. glutamicum cell by the phosphotransferase system ...
ORGANISM(S): Corynebacterium glutamicum 
2016-03-30 | E-GEOD-79690 | biostudies-arrayexpress
TranscriptomicsIL-10 from intestinal macrophages prevents excessive innate immune responses to bacteria by limiting IL-23 synthesis
Innate immune responses must be regulated in the intestine to prevent excessive inflammation. Here, using gene reporter mice, we show that a subset of mouse colonic macrophages constitutively produced the anti-inflammatory cytokine IL-10. In mice infected with Citrobacter rodentium, which is consid...
ORGANISM(S): Mus musculus 
2015-05-12 | E-GEOD-58677 | biostudies-arrayexpress
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