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MetabolomicsMetabolite profiling of Arabidopsis mutants of enzymes of lower glycolysis
We have previously shown that in Arabidopsis the three enzymes of lower glycolysis phosphoglycerate mutase (PGAM), enolase and pyruvate kinase form a complex which play an important role in co-sub-cellar localization the mitochondria to the chloroplast. Given that their metabolites of these mutants,...
2022-10-10 | MTBLS4066 | MetaboLights
UnknownProteome Analysis Reveals Extensive Light Stress-Response Reprogramming in the Seagrass Zostera muelleri (Alismatales, Zosteraceae) Metabolism.
Not available
S-EPMC5239797 | biostudies-literature
GenomicsAmplicon based single molecule footprinting in TC-1 DNMT TKO mESCs after RMCE
To quantify the contribution of specific transcription factor binding versus chromatin context in chromatin opening, we inserted libraries containing hundreds of CREs into a landing pad within a neutral chromatin environment, devoid of activating or repressive chromatin modifications, in mESCs using...
ORGANISM(S): Mus musculus 
2026-05-21 | E-MTAB-16658 | biostudies-arrayexpress
GenomicsAmplicon based single molecule footprinting in TC-1 DNMT TKO mESCs after RMCE and after 24h p300 inhibition
To quantify the contribution of specific transcription factor binding versus chromatin context in chromatin opening, we inserted libraries containing hundreds of CREs into a landing pad within a neutral chromatin environment, devoid of activating or repressive chromatin modifications, in mESCs using...
ORGANISM(S): Mus musculus 
2026-05-21 | E-MTAB-16659 | biostudies-arrayexpress
GenomicsAmplicon based single molecule footprinting in TC-1 DNMT TKO mESCs after RMCE - Mutant Libraries
To directly test how individual TFs combine their functions to open chromatin at specific loci, we used synthetic DNA sequences. We generated a library containing all combinations of TF-motif deletions for three CREs: a CTCF-bound region as a positive control (found in \"MutLib1\"), an enhancer with...
ORGANISM(S): Mus musculus 
2026-05-21 | E-MTAB-16657 | biostudies-arrayexpress
TranscriptomicsAdenoviral vector vaccination induces a conserved program of CD8+ T cell memory differentiation in mouse and man
Following exposure to vaccines, antigen-specific CD8+ T-cell responses develop as long-term memory pools. Novel vaccine strategies based on adenoviral vectors, e.g. those developed for HCV, are able to induce and sustain substantial CD8+ T-cell populations. How such populations evolve following vacc...
ORGANISM(S): Mus musculus 
2015-09-23 | E-GEOD-73314 | biostudies-arrayexpress
UnknownMethylomic changes in individuals with psychosis, prenatally exposed to endocrine disrupting compounds: Lessons from diethylstilbestrol.
Not available
S-EPMC5390994 | biostudies-literature
MetabolomicsNorbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFkB, MAPK and STAT3 activation and blocking metabolic reprogramming

Inflammation is thought to be a key cause of many chronic diseases and cancer. However, current therapeutic agents to control inflammation have limited long-term use potential due to various side-effects. This study aimed to examine norbergenin, a constituent of traditional anti-inflammatory reci...

2023-04-06 | MTBLS7127 | MetaboLights
TranscriptomicsTranscriptomic study (RNAseq) of Brachypodium distachyon ecotypes Bd21 and Bd2-3 under submergence stress
Purpose: The goal of this study is to compare the transcriptomes expressed during submergence stress of two Brachypodium distachyon ecotypes with contrasting survival under this stress. Bd21 is a submergence sensitive ecotype with EC50 of 2.5 days and Bd2-3 is a tolerant ecotype with EC50 of 4 days....
ORGANISM(S): Brachypodium distachyon 
2016-01-04 | E-GEOD-74222 | biostudies-arrayexpress
UnknownEffect of Inulin on Proteome Changes Induced by Pathogenic Lipopolysaccharide in Human Colon.
Not available
S-EPMC5222518 | biostudies-literature
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