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TranscriptomicsOncogenic SDH mutation underlies global epigenomic instability in gastrointestinal stromal tumor
We have discovered a striking connection between mitochondrial dysfunction and epigenomic instability, manifested by global biallelic DNA cytosine 5-methylation and loss of 5-hydroxymethycytosine within succinate dehydrogenase (SDH)-null gastrointestinal stromal tumors (GIST) relative to those beari...
ORGANISM(S): Homo sapiens 
2013-05-22 | E-GEOD-34387 | biostudies-arrayexpress
MetabolomicsRhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells (LC-MS)

Circadian clocks coordinate mammalian behaviour and physiology enabling organisms to anticipate 24-hour cycles. Transcription-translation feedback loops are thought to drive these clocks in most of mammalian cells. However, red blood cells (RBCs), which do not contain a nucleus, and cannot perfor...

2020-11-13 | MTBLS1285 | MetaboLights
MetabolomicsRhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells (GC-MS)

Circadian clocks coordinate mammalian behaviour and physiology enabling organisms to anticipate 24-hour cycles. Transcription-translation feedback loops are thought to drive these clocks in most of mammalian cells. However, red blood cells (RBCs), which do not contain a nucleus, and cannot perfor...

2020-11-13 | MTBLS1286 | MetaboLights
UnknownIndividual Differences in CD4/CD8 T-Cell Ratio Trajectories and Associated Risk Profiles Modeled From Acute HIV Infection.
Not available
S-EPMC9553252 | biostudies-literature
UnknownVaccination against HPV-Associated Neoplasias: Recommendations from the Current S3 Guideline of the HPV Management Forum of the Paul-Ehrlich Society - AWMF Guidelines, Registry No. 082-002 (short version), valid until Dec. 31st, 2018.
Not available
S-EPMC4812874 | biostudies-literature
UnknownValue of [18F]-FDG positron emission tomography in patients with recurrent glioblastoma receiving bevacizumab.
Not available
S-EPMC7236386 | biostudies-literature
UnknownMalate as a key carbon source of leaf dark-respired CO2 across different environmental conditions in potato plants.
Not available
S-EPMC4566975 | biostudies-literature
UnknownATRX loss in adult gliomas lacking H3 alterations or IDH mutations, an exceptional situation for exceptional diagnoses: the experience of Sainte-Anne hospital.
Not available
S-EPMC12164129 | biostudies-literature
UnknownThe minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition.
Not available
S-EPMC8927835 | biostudies-literature
ProteomicsSuccinylome-controlled antibiotic resistance in MRSA - Succinylome
A sucC and a sucD mutant from the Nebraska Transposon Mutant Library (NTML, Strain NE569 and NE1770) were found to be susceptible to cefoxitin and oxacillin when other mutations in TCA cycle genes did not affect their resistance to these antibiotics. The SucC strain (Strain NE569) accumulated Succin...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
2021-03-02 | MSV000086971 | MassIVE
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