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ProteomicsGenome-scale analysis reveals paralog lethality as a vulnerability of chromosome 1p loss in cancer
Viswanathan SR, Nogueira MF, Buss CG, Krill-Burger JM, Wawer MJ, Malolepsza E, Choi PS, Berger A, Shih J, Tanenbaum B, Strathdee CA, Tamayo P, Pedamallu CS, Vazquez F, Lage K, Carr SA, Schenone M, Bhatia SN, Cherniack AD, Tsherniak A, Hahn WC, Meyerson M. Nature Genetics 2018. Chromosome arm-level d...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-04-19 | MSV000082292 | MassIVE
UnknownSynthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.
Not available
S-EPMC8374858 | biostudies-literature
UnknownCohesin mutations alter DNA damage repair and chromatin structure and create therapeutic vulnerabilities in MDS/AML.
Not available
S-EPMC7934867 | biostudies-literature
UnknownGenome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer.
Not available
S-EPMC6143899 | biostudies-literature
UnknownPhosphate dysregulation via the XPR1-KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer.
Not available
S-EPMC9246846 | biostudies-literature
UnknownDefining a Cancer Dependency Map.
Not available
S-EPMC5667678 | biostudies-literature
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