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UnknownTreatment with PCSK9 monoclonal antibodies is associated with discontinuation of oral lipid lowering therapy.
Not available
S-EPMC12714381 | biostudies-literature
TranscriptomicsGenes involved in synthesis of lipoteichoic acids are induced when Bifidobacterium animalis subsp. lactis BB12 is incubated with Human Enterocyte-Like Caco-2 Cells
Bifidobacterium animalis subsp. lactis BB12 is a widely used probiotic bacterium. However the molecular mechanism by which this bacterium confers positive health effects to the host is largely unknown. The importance of lipoteichoic acids (LTA) in the cross-talk between the bacteria and human entero...
ORGANISM(S): Bifidobacterium animalis subsp. lactis BB-12 
2012-07-31 | E-GEOD-21588 | biostudies-arrayexpress
TranscriptomicsTGF-b Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium
Digital gene expression tag profiling of P19CL6 cell model during differentiation to cardiomyocytes Four replicates were anlyzed at five time-points during differentiation; day 1, day 4, day 7, day 10 and day 14. Spontanously beating cardiomyocytes was observed at day 14 Spreadsheet with Log2 differ...
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-47656 | biostudies-arrayexpress
MetabolomicsTranscriptomics and metabolomics of engineered Synechococcus elongatus during photomixotrophic growth

BACKGROUND: Converting carbon dioxide (CO2) into value-added chemicals using engineered cyanobacteria is a promising strategy to tackle the global warming and energy shortage issues. However, most cyanobacteria are autotrophic and use CO2 as a sole carbon source, which makes it h...

2022-03-21 | MTBLS2825 | MetaboLights
TranscriptomicsSOCS2 expression correlates with tumor malignancy, exerts growth promoting effects and is enhanced by androgens in prostate cancer
Deregulation of cytokine- and growth factor signaling due to altered expression of endogenous regulators is well recognized in prostate and other cancers. Suppressor of cytokine signaling 2 (SOCS2) is a key regulator of growth hormone, IGF and prolactin signaling, that have been implicated in carcin...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-50936 | biostudies-arrayexpress
TranscriptomicsITIH5
In order to identify patterns of gene expression that are associated with the putative tumor suppressor gene ITIH5 mediated suppression of breast cancer metastatic growth, we performed a transcriptomic micro-array analysis of the MDA-MB-231 wildtype, three independent highly aggressive MDA-MB-231-mo...
ORGANISM(S): Homo sapiens 
2017-01-30 | E-MTAB-1813 | biostudies-arrayexpress
UnknownThe Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor.
Not available
S-EPMC5413573 | biostudies-literature
TranscriptomicsHuman PC-3 prostate cancer cells: Control (shNTC; non-target shRNA) vs. shETV4 knock down (shETV4)
Transcriptional profiling of human PC-3 prostate cancer cells lentivirally infected with non-target control (NTC) short hairpin (sh)RNA comparing with lentivirally shRNA mediated human ETV4 knock-down. Cells were either cultured for 24 hours at 20% oxygen tension or 0.2% oxygen. Goal was to determin...
ORGANISM(S): Homo sapiens 
2011-12-06 | E-GEOD-32385 | biostudies-arrayexpress
TranscriptomicsThe Epigenome of Spermatozoa is Affected in Obesity and Dynamically Changes after Bariatric Surgery [Lean/Obese MNase]
Obesity is a heritable disorder, with children of obese fathers at higher risk of developing obesity.  Environmental factors epigenetically influence somatic tissues, but the contribution of these factors to the establishment of epigenetic patterns in human gametes is unknown. Here, we hypothesized...
ORGANISM(S): Homo sapiens 
2015-12-04 | E-GEOD-74426 | biostudies-arrayexpress
UnknownGaps and discontinuation of statin treatment in Norway: potential for optimizing management of lipid lowering drugs.
Not available
S-EPMC9683394 | biostudies-literature
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