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ProteomicsShotgun proteomics on sterile culture supernatant from S. aureus clinical isolates
Shotgun proteomics on sterile culture supernatant from S. aureus clinical isolates to determine proteins associated with pro-inflammatory phenotype.
ORGANISM(S): Staphylococcus aureus 
2022-02-22 | PXD028604 | Pride
S. aureus Shotgun proteomics Culture supernatant Secretome Lc-ms/ms 
ProteomicsAntibody-free multiplex measurement of 23 human cytokines in primary cell culture secretome using targeted multiple reaction monitoring mass spectrometry
Cytokines are key mediators of inflammation that commonly serve as biomarkers to monitor immune responses and inflammatory disease. Cytokines are commonly measured by immunoassays, which have limited multiplexing capacity, are costly and can exhibit cross-reactivity. Although multiple reaction monit...
ORGANISM(S): Homo Sapiens 
2020-02-19 | PXD015448 | panorama
ProteomicsSkin cancer-associated S. aureus downregulates DNA repair mechanisms, and promotes oxidative stress and DNA damage in human keratinocytes
Actinic keratoses (AK) are premalignant lesions common on photo-damaged skin that, over time, can progress to squamous cell carcinoma (SCC). A high bacterial load of Staphylococcus aureus is associated with AK and SCC but it is unknown whether this has a direct impact on skin cancer development. To ...
ORGANISM(S): Staphylococcus Capitis Staphylococcus Aureus Staphylococcus Epidermidis Staphylococcus 
2022-05-17 | PXD031676 | panorama
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