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TranscriptomicsLinkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3
OBJECTIVE: MEIS1, a HOX cofactor, collaborates with multiple HOX and NUP98-HOX fusion proteins to accelerate the onset of acute myeloid leukemia (AML) through largely unknown molecular mechanisms. MATERIALS AND METHODS: To further resolve these mechanisms, we conducted a structure-function analysis ...
ORGANISM(S): Mus musculus 
2009-04-09 | E-GEOD-15541 | biostudies-arrayexpress
UnknownTargeted therapies through microRNAs: pulp or fiction?
Not available
S-EPMC3573433 | biostudies-literature
UnknownFLAMSA-RIC for Stem Cell Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndromes: A Systematic Review and Meta-Analysis.
Not available
S-EPMC6780116 | biostudies-literature
UnknownMaintenance With Hypomethylating Agents After Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Systematic Review and Meta-Analysis.
Not available
S-EPMC8887643 | biostudies-literature
TranscriptomicsNotch regulated miRNAs in human T-ALL cell line
In an attempt to identify miRNAs regulated by oncogenic Notch signaling, we performed miRNA profiling of human T-cell acute lymphoblastic leukemia (T-ALL) cells with or without the treatment of γ-secretase inhibitor (GSI) to block Notch signaling. We found miR-223 levels to increase after GSI treatm...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-35993 | biostudies-arrayexpress
UnknownRedefining high risk multiple myeloma with an APOBEC/Inflammation-based classifier.
Not available
S-EPMC11073955 | biostudies-literature
UnknownProspective identification of resistance mechanisms to HSP90 inhibition in KRAS mutant cancer cells.
Not available
S-EPMC5352352 | biostudies-literature
UnknownThe long non-coding RNA Cancer Susceptibility 15 (CASC15) is induced by isocitrate dehydrogenase (IDH) mutations and maintains an immature phenotype in adult acute myeloid leukemia.
Not available
S-EPMC7556616 | biostudies-literature
UnknownLipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo.
Not available
S-EPMC7116733 | biostudies-literature
TranscriptomicsThe role of Hoxa9 and Meis1 in development of acute myeloid leukemia (mRNA)
OBJECTIVE: MEIS1, a HOX cofactor, collaborates with multiple HOX proteins, such as HOXA9, to accelerate the onset of acute myeloid leukemia (AML) through largely unknown molecular mechanisms. To further resolve these mechanisms, we conducted a structure-function analysis of Meis1 and gene expression...
ORGANISM(S): Mus musculus 
2016-09-01 | E-GEOD-75272 | biostudies-arrayexpress
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