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TranscriptomicsThe addition of chromosome 8 leads to characteristic dysregulation of gene expression on all chromosome and transformed-associated phenotypes
To examain effects of trisomy 8 on gene expression in normal human cells, we have employed whole genome microarray expression profiling. To study the effects of aneuploidy in normal human cells, we generated cells which are artificially trisomic chromosome 8 (trisomy 8) using human primary fibroblas...
ORGANISM(S): Homo sapiens 
2011-10-07 | E-GEOD-28076 | biostudies-arrayexpress
TranscriptomicsPITX1 suppresses TERT transcription
Using microcell-mediated chromosome transfer (MMCT) into the mouse melanoma cell line, B16F10, we have previously found that human chromosome 5 carries a gene, or genes, that can negatively regulate TERT expression. To identify the gene responsible for the regulation of TERT transcription, we perfor...
ORGANISM(S): Mus musculus 
2010-09-10 | E-GEOD-23216 | biostudies-arrayexpress
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