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TranscriptomicsSingle-cell immune repertoire sequencing of bone marrow plasma cells following infection and immunizations
We performed single-cell transcriptome and antibody repertoire sequencing of bone marrow plasma cells following protein (OVA and TNFR2) immunizations or infection with high dose LCMV clone 13.
ORGANISM(S): Mus musculus 
2021-12-01 | E-MTAB-11096 | biostudies-arrayexpress
TranscriptomicsDefective removal of ribonucleotides from DNA promotes systemic autoimmunity
Constitutive low level DNA damage in RNASEH2 deficiency is linked to innate immune activation. Hierarchical clustering of over 16000 transcripts revealed remarkably similar profiles in patients with lupus erythematosus and patients with AGS with up-regulation of genes involved in DNA damage signalin...
ORGANISM(S): Homo sapiens 
2014-12-15 | E-GEOD-63755 | biostudies-arrayexpress
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