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ProteomicsPrion MRM assay development and clinical study
Therapies currently in preclinical development for prion disease seek to lower prion protein (PrP) expression in the brain. Trials of such therapies are likely to rely on quantification of PrP in cerebrospinal fluid (CSF) as a pharmacodynamic biomarker and possibly as a trial endpoint. Studies using...
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus Macaca Fascicularis 
2019-11-19 | PXD014781 | panorama
TranscriptomicsDistinct tumorigenic pathways within hereditary nonpolyposis colorectal cancer
Gene expression profiling has discriminated between sporadic microsatellite instable (MSI) and microsatellite stable (MSS) colorectal cancers (CRCs), whereas the expression pattern of familial colorectal cancer type X (FCCTX) and Lynch syndrome (LS) associated CRCs remain largely unknown. The purpos...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-36335 | biostudies-arrayexpress
ProteomicsWorkingtitle HLA-B*57:01 CBZ EPX impact
Impact of CBZ and EPX treatment on a with HLA-B*57:01 tranduced cell line compared to the parental cell line
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD037502 | Pride
Hla-b*57:01 human hla cbz epx 
ProteomicsConsistency across multi-omics layers in a drug-perturbed gut microbial community
Here we map the molecular response of a synthetic community of 32 human gut bacteria to three non-antibiotic drugs by using five omics layers, namely 16S rRNA gene profiling, metagenomics, metatranscriptomics, metaproteomics, and metabolomics. Using this controlled setting, we find that all omics me...
ORGANISM(S): metagenome 
2022-12-13 | PXD036445 | Pride
Multi-omics proteomics metagenomics metatranscriptomics community drug chlorpromazine niclosamide metformin gut microbiome microbiota 
UnknownStandardizing data reporting in the research community to enhance the utility of open data for SARS-CoV-2 wastewater surveillance.
Not available
S-EPMC8459677 | biostudies-literature
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