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MetabolomicsMetabolomics Characterization of Human Calcific Aortic Valve Stenosis

BACKGROUND: Calcific aortic valve stenosis (CAVS) is the most prevalent valvular heart disease in developed countries with significant morbidity and mortality. Given the poor understanding of the pathophysiological processes leading to CAVS, we utilized a joint non-targeted metab...

2020-02-03 | MTBLS1267 | MetaboLights
UnknownSkeletal dysplasias: A radiographic approach and review of common non-lethal skeletal dysplasias.
Not available
S-EPMC4209426 | biostudies-literature
MetabolomicsEFO: In preparation - Early Metabolic Predictors of Type 2 Diabetes Mellitus in Normoglycemic Adults: Insights from Six-Year Prospective Cohort Study

INTRODUCTION: Type 2 Diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia, often preceded by latent metabolic disruptions. Early detection of metabolic alterations can facilitate timely intervention to delay or prevent T2DM onset. Metaboli...

2025-08-04 | MTBLS10965 | MetaboLights
TranscriptomicsUnderstanding the complexity of fruit ripening by transcriptome analysis of rin mutant fruit
[original title] Understanding the complexity of fruit ripening by transcriptome analysis of rin mutant fruit and in silico analysis of promoters of differentially regulated genes A tomato MADS-box transcription factor, LeMADS-RIN, controls fruit ripening and mutation in this gene results in non-ri...
ORGANISM(S): Solanum lycopersicum 
2012-02-29 | E-GEOD-20720 | biostudies-arrayexpress
UnknownEngineering DNA vaccines against infectious diseases.
Not available
S-EPMC7105045 | biostudies-literature
TranscriptomicsA genome-wide perspective of miRNAome in response to high temperature, salinity and drought stresses in Brassica juncea (Czern) L.
Purpose: To identify high temperature, sailinity and drought-responsive miRNAs at genome wide level in B. juncea var varuna. Results: In this study four small RNA libraries viz. B. juncea control (BJC), B. juncea high temperature stressed (BJH), B. juncea salinity stressed (BJS) and B. juncea drough...
ORGANISM(S): Brassica juncea 
2014-08-20 | E-GEOD-53242 | biostudies-arrayexpress
ProteomicsDiscovery and Development of CD70 As a Cellular Therapy Target in High Risk Multiple Myeloma
Even in the BCMA CAR-T era, multiple myeloma (MM) patients with high-risk genotypes have the poorest outcomes. We thus leveraged MMRF CoMMpass data to identify potential novel surface immunotherapeutic targets in high-risk MM. As described below, we focused on CD70, an immunotherapeutic target known...
ORGANISM(S): Homo sapiens (Human) 
2025-11-27 | PXD048492 | Pride
Car-t Cd 70 Multiple myeloma Immunotherapy 
Unknowncis-Bis(2,2'-bipyridine-κN,N')dichloridocobalt(II) trihydrate.
Not available
S-EPMC3099996 | biostudies-literature
Unknowncis-Aqua-chloridobis(1,10-phenanthroline-κN,N')cobalt(II) chloride 2.5-hydrate.
Not available
S-EPMC2971197 | biostudies-literature
UnknownPermissive Cardiotoxicity in HER2-Positive Metastatic Breast Cancer With Moderate Left Ventricular Dysfunction
Not available
S-EPMC12932988 | biostudies-literature
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