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TranscriptomicsA 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysema following smoking cessation or switching to e-vapor products.
Cigarette smoking causes serious diseases, including lung cancer, heart disease, and emphysema. While cessation remains the most effective approach to minimize smoking-related disease, alternative non-combustible tobacco-derived nicotine containing products may reduce disease risks among those unabl...
ORGANISM(S): Mus musculus 
2021-03-18 | E-MTAB-9597 | biostudies-arrayexpress
UnknownSeasonal variation in expression pattern of genes under HSP70 : Seasonal variation in expression pattern of genes under HSP70 family in heat- and cold-adapted goats (Capra hircus).
Not available
S-EPMC3982034 | biostudies-literature
TranscriptomicsExpression data in response to pepper leaf curl virus (PepLCV) infection in Chilli pepper at three leaf stage
A comparative study to determine the pepper leaf curl virus resistance machanism between resistant and susceptible genotypes at three leaf stage. To study the molecular mechanism of pepper leaf curl virus (PepLCV) resistance, pepper plants were exposed to PepLCV through artificial inoculation and hy...
ORGANISM(S): Capsicum annuum 
2012-10-11 | E-GEOD-41131 | biostudies-arrayexpress
TranscriptomicsA 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared to cigarette smoke.
Smoking cigarettes is harmful to the cardiovascular system. Considerable attention has been paid to the reduced harm potential of alternative nicotine-containing inhalable products such as e-cigarettes. We investigated the effects of E-vapor aerosols or cigarette smoke (CS) on atherosclerosis progre...
ORGANISM(S): Mus musculus 
2020-05-12 | E-MTAB-8578 | biostudies-arrayexpress
ProteomicsDifferentially expressed proteins in Human Primary Keratinocytes upon IL-9 stimulation
HPKs from 3-5 healthy individual donors were pre-stimulated with TGFb (10ng/ml) plus IL-4 (20ng/ml) to upregulated the IL-9R (Das et al., 2019). Next day, HPKs were stimulated with IL-9 (50ng/ml) or in combination with IFNg (10ng/ml) for 24 hours at 37 degree C with 5% CO2. Sample preparation for L...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-28 | MSV000086776 | MassIVE
TranscriptomicsMicroarray Expression profiling of susceptible (CO-3) and resistant (EC-520061) genotype of tomato in response to Early Blight pathogen after 24hrs of inoculation
A comparative study ware made to know the Early Blight resistance mechanism between resistant and susceptible plants at vegetative stage. Transcriptional changes during compatible and resistant reaction between A. solani and tomato genotypes have been identified using Affymetrix tomato gene chips. R...
ORGANISM(S): Solanum lycopersicum 
2015-07-29 | E-GEOD-71428 | biostudies-arrayexpress
GenomicsEvaluation of methyl-binding domain based enrichment approaches revisited
A comparison of methylMiner and MethylCap, two methylation enrichment kits The main analysis include two individuals (mice) in technical duplicates from various lab/technical conditions. The results are compared with previous studies of two human samples from a number of lab/technical conditions (hu...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-64144 | biostudies-arrayexpress
TranscriptomicsExpression data in response to abiotic stresses in tomato at flowering stage
A comparative study ware made to know the abiotic stress tolerance machanism between tolerant and susceptible plants at flowering stage. The tolerance in response to abiotic stresses are sum of expression of thousands of genes at a particular stage. Tomato plants were exposed to drought and heat str...
ORGANISM(S): Solanum lycopersicum 
2010-06-23 | E-GEOD-22304 | biostudies-arrayexpress
TranscriptomicsIdentification of differentially expressed genes in Fibrogenesis imperfecta ossium via Global microarray analysis
Global microarray was performed from Trans-Iliac Bone biopsy from the patient with clinically characterized Fibrogensis imperfecta ossium (FIO). A 40-year-old male patient with clinically characterized Fibrogensis imperfecta ossium (FIO) includes fragility fracture with osteomalacia (Losserâ??s zo...
ORGANISM(S): Homo sapiens 
2016-07-31 | E-GEOD-43861 | biostudies-arrayexpress
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