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ProteomicsMuscle-specific increased expression of JAG1 improves the skeletal muscle phenotype in dystrophin-deficient mice
Therapeutic strategies for Duchenne muscular dystrophy (DMD) will likely require complementary approaches. One possibility is to explore genetic modifiers that improve muscle regeneration and function. The beneficial effects of the overexpression of Jagged-1 were described in escaper golden retrieve...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-30 | PXD068185 | Pride
Duchenne muscular dystrophy  jagged-1  mouse model  genetic modifier  physiology 
TranscriptomicsGene expression profiles in muscle tissue from FSHD patients
Muscle biopsies from biceps and deltoid were taken from 5 patients with FSHD, 5 asymptomatic carriers and 5 normal controls. The genome-wide expression patterns were compared using Affymetrix U133 Plus 2.0 chips. Keywords: Facioscapulohumeral, FSHD, muscular dystrophy Gene expression profiles were ...
ORGANISM(S): Homo sapiens 
2009-03-04 | E-GEOD-15090 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of zebrafish mononuclear myogenic cells (zMNCs) during myogenic differentiation
Analysis of the transcriptome of zebrafish mononuclear myogenic cells (zMNCs) during myogenic differentiation. The main goal is to identify the similarities of zMNC myogenic differentiation with that of mammalian myoblast differentiation. Critical time points were used to identify a switch from the ...
ORGANISM(S): Danio rerio 
2010-04-07 | E-GEOD-19754 | biostudies-arrayexpress
GenomicsThe Gene Partnership (TGP) - eMERGE Data

The Gene Partnership (TGP) is a prospective longitudinal registry at Boston Children's Hospital (BCH) to study the genetic and environmental contributions to childhood health and disease, collect genetic information on a large number of children who have been phenotyped, and implement the Inf...

phs000495.v1.p1 | EGA
UnknownComparative Effects of Glucose-Lowering Medications on Kidney Outcomes in Type 2 Diabetes: The GRADE Randomized Clinical Trial.
Not available
S-EPMC10203973 | biostudies-literature
UnknownFostamatinib for Hospitalized Adults With COVID-19 and Hypoxemia: A Randomized Clinical Trial.
Not available
S-EPMC11615712 | biostudies-literature
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