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TranscriptomicsExpression data from tumor and normal epithelium derived from BRCA1-mutation carriers
Microarrays were used to determine relative global gene expression changes in WT and BRCA1-mutation carrier breast epithelium as well as tumors created from WT and BRCA1-mutation carrier breast epithelial cells. Total RNA was isolated from freshly dissociated mammary epithelilal cells obtained from ...
ORGANISM(S): Homo sapiens 
2011-02-04 | E-GEOD-25835 | biostudies-arrayexpress
TranscriptomicsExpression Data from Mouse Mammary Gland Adipose Stroma
Adipose stroma in the mouse mammary gland undergoes remodeling throughout the 5 stages of development. These include nulliparous (virgin;never been pregnant), pregnant, lactating, involuting and regressed. We used a microarry to determine the changes in gene expression during gland development. Mou...
ORGANISM(S): Mus musculus 
2013-12-06 | E-GEOD-53044 | biostudies-arrayexpress
TranscriptomicsGenome Wide Expression of Mammary Epithelial Populations in Slug (SNAI2) WT vs Slug Null Mice
This experiment shows differential expression of genes in the luminal, basal and stromal subpopulations from SNAI2+/+ and SNAI2 LacZ/LacZ mammary epithelial cells. Luminal, basal and stromal populations were sorted from SNAI2+/+ and SNAI2 LacZ/LacZ mammary epithelial cells based on expression of CD4...
ORGANISM(S): Mus musculus 
2014-03-08 | E-GEOD-55620 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HMLER breast cancer cells treated with paclitaxel and salinomycin-treated HMLER breast cancer cells
Screens for agents that specifically kill epithelial cancer stem cells (CSCs) have not been possible due to the rarity of these cells within tumor cell populations and their relative instability in culture. We describe here an approach to screening for agents with epithelial CSC-specific toxicity. W...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-17215 | biostudies-arrayexpress
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