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ModelsKuroda2001_NO_cGMP_Pathway
This model of sGC is based on the paper by Kuroda S. et al. J Neurosci. (2001) 21(15):5693-702 . This models features the activation of sGC by NO, synthesis of cGMP, activity of PKG and PP2A in the synapse. The rates and concentrations have been taken from literature. It contains only the...
2005-01-01 | MODEL4780181279 | BioModels
ModelsSasagawa2005_MAPK
This a model from the article: Prediction and validation of the distinct dynamics of transient and sustained ERK activation. Sasagawa S, Ozaki Y, Fujita K, Kuroda S Nat. Cell Biol.[2005 Apr; Volume: 7 (Issue: 4 )]: 365-73 15793571, Abstract: ...
2024-09-02 | BIOMD0000000049 | BioModels
ModelsKubota2012_InsulinAction_AKTpathway
This model is from the article: Temporal Coding of Insulin Action through Multiplexing of the AKT Pathway. Kubota H, Noguchi R, Toyoshima Y, Ozaki Y, Uda S, Watanabe K, Ogawa W, Kuroda S. Mol Cell. 2012 Jun 29;46(6):820-32. 22633957 , ...
2005-01-01 | MODEL1204060000 | BioModels
ProteomicsProteome analysis of mouse liver and skeletal muscle
The liver and skeletal muscle were collected from 10-week-old wild-type and ob/ob mice fasted for 16 hours. Tissues were frozen immediately and lysed with 0.5 mL of a solution containing 50 mM Tris-HCl pH8.8, 2%SDS, and 7 M urea, and then subjected to ultrasonic treatment with a Bioruptor (Digaenode...
ORGANISM(S): Mus Musculus (mouse) 
2021-03-03 | PXD020656 | JPOST Repository
ModelsFujita2010_Akt_Signalling_EGF
EGF dependent Akt pathway model made by Kazuhiro A. Fujita. This is the EGF dependent Akt pathway model described in: Decoupling of receptor and downstream signals in the Akt pathway by its low-pass filter characte...
2024-09-02 | BIOMD0000000262 | BioModels
ModelsFujita2010_Akt_Signalling_EGFRinhib
Akt pathway model with EGFR inhibitor made by Kazuhiro A. Fujita. This is the Akt pathway model with an EGFR inhibitor described in: Decoupling of receptor and downstream signals in the Akt pathway by ...
2024-09-02 | BIOMD0000000264 | BioModels
ModelsFujita2010_Akt_Signalling_NGF
NGF dependent Akt pathway model made by Kazuhiro A. Fujita. This is the NGF dependent Akt pathway model described in: Decoupling of receptor and downstream signals in the Akt pathway by its low-pass ...
2024-09-02 | BIOMD0000000263 | BioModels
ProteomicsPhosphoproteome data of WT and ob/ob mice liver during starvation
Ten-week-old male mice (WT and ob/ob) were starved for 0, 2, 4, 6, 8, 12, 16, and 24 hours and liver samples were collected. Total proteins extracted during sample preparation of metabolomic analysis were subjected to the following phosphoproteomic analysis. As described above, 2 mg of protein solut...
ORGANISM(S): Mus Musculus (mouse) 
2025-05-20 | PXD053026 | JPOST Repository
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 1 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000540 | BioModels
ModelsYugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2
Yugi2014 - Insulin induced signalling (PFKL phosphorylation) - model 2 Insulin induces phosphorylation and activation of liver-type phosphofructokinase 1, which thereby controls a key reaction in glycolysis. This mechanism is revealed using the mathematical model. In this model, the PFKL ph...
2024-09-02 | BIOMD0000000541 | BioModels
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